Kyprios is one of only eight remaining entries in Saturday's Prix du Cadran at Longchamp, with just one contender trained in France.
Aidan O’Brien’s star stayer won the contest in remarkable circumstances in 2022 when, despite hanging across the track in the home straight, he came home 20 lengths clear.
After injury restricted him to just two outings last season, Kyprios has won each of his run races this year.
O’Brien has also left in Continuous, who has the option of running in the Prix de l’Arc de Triomphe, and Point Lonsdale.
Either side of Kyprios’ win, the Cadran has been claimed by Alan King’s Trueshan, and the veteran is once again lined up for the race.
John and Thady Gosden’s Sweet William finally bagged a big prize at Doncaster last time out and could run, with Mark Prescott’s Miss Cynthia and Andrew Balding’s Coltrane also in contention.
The only home-trained potential runner is Christophe Ferland’s Double Major.
William Haggas is searching for a third successive win in the Prix de Royallieu with Sea Theme.
Sea La Rosa and Sea Silk Road have provided Haggas with Group One victories in a race that has not been won by a French-trained runner since 2017.
Henry de Bromhead’s Term Of Endearment, David Menuisier’s Caius Chorister and O’Brien’s Port Fairy are among 16 left in.
There are 11 left in the Prix Dollar, including Brian Meehan’s Jayarbee, the Owen Burrows-trained Anmaat and Ed Walker’s Almaqam.
Haggas’ Maljoom and Karl Burke’s Holloway Boy are among 13 in the Prix Daniel Wildenstein, while St Leger runner-up Illinois is one of 11 in the Prix Chaudenay.
There are supplementary entry stages for all races on Wednesday.
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