Roma held off AC Milan to advance to the semi-finals of the Europa League on Thursday night.
Daniele De Rossi's side, who won the first leg 1-0, scored two quickfire goals through Gianluca Mancini and Paulo Dybala to strengthen their advantage.
Despite Mehmet Zeki Celik's red card for a late challenge on Rafael Leao and Matteo Gabbia pulling one back in the 85th minute, the hosts managed to see out the match.
Marseille had to rely on penalties to claim their last-eight win over Benfica.
Benfica went to Stade Velodrome with a 2-1 advantage. Faris Moumbagna opened the scoring for the hosts but both defences proved to be stubborn as the match went the distance after extra-time.
Antonio Silva and Angel Di Maria missed from 12 yards before Luis Henrique scored the decisive spot-kick to send the French club through.
Elsewhere Liverpool crashed out after they failed to turn around their 3-0 first-leg defeat to Atalanta despite winning 1-0 at Gewiss Stadium.
Jurgen Klopp's men took the lead from the spot in the seventh minute through Mohamed Salah but could not find the goals needed as they fell to a 3-1 aggregate loss in the quarter-finals.
West Ham were knocked out by Bundesliga champions Bayer Leverkusen at London Stadium, also going out 3-1 on aggregate.
The Hammers gave themselves hope, both in the tie and of inflicting a first defeat of the season on Leverkusen, courtesy of Michail Antonio's first-half goal.
But it was not enough as Leverkusen scored late on through Jeremie Frimpong.
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